Recipients Sergio Henrique Ferreira
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 Sergio Henrique Ferreira Premio México de Ciencia y Tecnología 1999
This group of medicines constitutes today a family of drugs used successfully for the control of hypertension, cardiac insufficiency and lesions from infarct of the myocardium, known as inhibitors of the angiotensin converting enzyme or ACE. Sergio Henrique Ferreira is also known internationally for his contribution in the area of anti inflammatory painkillers. His proposition dealing with the mechanism of the analgesic action of aspirin, widely accepted today, stems from that time. He proposed that the analgesic action of anti inflammatory non steroids was the result of avoiding sensitization of the pain receptors, as a consequence of inhibiting the synthesis of prostaglandine. Today, Ferreira studies a phenomenon of retrograde sensitization of the primary neuron, he described. This sensitization, occurring due to the liberation of glutamate in the spinal cord, seems to be fundamental for the maintenance of the inflammatory hyperalgesia of the primary peripheral neuron. This concept reinforces the possibility of finding peripheral analgesics as powerful as those acting upon the central nervous system. Dr. Ferreira is also a remarkable scientific leader in Brazil, where he has furthered the Academia Nacional de Ciencias [National Academy of Sciences] of Brazil and the Consejo Brasileño de Ciencia y Tecnología [Brazilian Council of Science and Technology]. In his field, he founded the Sociedad Brasileña de Farmacología y Terapéutica [Brazilian Society of Pharmacology and Therapeutics] as well as the Sociedad Brasileña para el Progreso de la Ciencia (SBPC) [Brazilian Society for the Progress of Science]. Ferreira received the CIBA Award for Hypertension Research in 1983, granted by the American Heart Association and the Award for Hypertension Research of the American Society for Clinical Pharmacology and Therapeutics. He has also received the TWAS Award, the Orden Nacional del Mérito Científico [National Order of Scientific Merit] of Brazil, and was recognized by his country as one of the 10 best Brazilian doctors of the 20th Century. He has published over 200 research papers in the best international scientific journals and 2 classic books on inflammation. He participates in the world’s most important societies and as arbiter for highly respected scientific journals of pharmacology. Has presided the Federation Society for Experimental Biology and has directed the Instituto Nacional de Control de Calidad en Salud, Instituto Oswaldo Cruz [National Institute of Health Quality Control, Oswaldo Cruz Institute] of Río de Janeiro. He is a Foreign Fellow of the Academy of Sciences of the United States and was awarded the Premio México de Ciencia y Tecnología 1999 [1999 Mexico Award for Science and Technology]. |
